a tool for identifying drug-targetable redox-active disulphides

Acylcarnitine hydrolase

Intramolecular

Cysteine 97 and cysteine 125

A redox-regulated disulphide may form within Acylcarnitine hydrolase between cysteines 97 and 125.

Details

Redox score ?

81

PDB code

Structure name

crystal structure of mouse ces2c

Structure deposition date

2022-08-31

Thiol separation (Å)

2

Half-sphere exposure sum ?

82

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

97

Residue number B

125

Peptide name

Acylcarnitine hydrolase

Ligandability

Cysteine 97 of Acylcarnitine hydrolase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 125 of Acylcarnitine hydrolase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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